Thanks to Dr. Guy for today’s Morning Report (presented on 4/9/2012)!
Central Retinal Artery Occlusion
Epidemiology:
- 55% mortality rate over 9 years
- 2% bilateral involvement
- mean age 62
Pathophysiology:
- emboli in retinal artery/ branches
- ophthalmic artery from intraorbital branch of internal carotid artery
- ischemia and edema
- irreversible cell injury occurs after 90-100 minutes
Presentation:
- acute painless vision loss
- non-progressive vision loss
- branch retinal artery occlusion:
- Amaurosis fugax- transient visual acuity loss preceding persistent loss of vision
- peripheral vision field loss
Risk factors:
- Systemic hypertension seen in 2/3 of patients
- atherosclerosis
- myopia
- DM
- CAD
- atrial fibrillation
- valvular disease ¼
- cardiac abnormalities
- ss disease
- ocd
- vasculitis
- embolism
- cholesterol, calcific, bacteria, endocarditis, coaguloopathies, antiphospholilipid syndromes
Exam:
- boxcar appearance of the blood column can be seen in both arteries and vein
- afferent pupillary defect
- cherry red spot and ground glass retina- 1 hour after development
- pale optic disk seen days to weeks after event
- emboli seen 20%
Management:
- Emergency- call ophthalmology
- Controversy exists regarding the optimal window of treatment in humans
- Conservative approach involves treatment up to 24 hours
- Directed towards lowering IOP and increasing perfusion
- Only 25% regain baseline vision
- Give O2, peripheral thrombolytics, ocular massage, aspirin, hyperbarics
- Long term risk modifications
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The views expressed on this blog are the author's own and do not reflect the views of their employer. Please read our full disclaimer here. Any references to clinical cases refer to patients treated at a virtual hospital, Janus General Hospital.
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Jay Khadpe MD
Editor in Chief of "The Original Kings of County"
Assistant Professor of Emergency Medicine
Assistant Residency Director
SUNY Downstate / Kings County Hospital
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