Case #7, Answer

 

Case Recap: Old lady with hypotension, tachycardia and JVD…

I think we all agree that this person is sick. Prior to pondering the wide differential do the Basics: 2 Large Bore IVs, O2 NC vs NRB, Monitor, assess airway

 

My Top Three Differential Diagnoses

1. Cardiac Tamponade

2. Massive PE

3. Inferior Wall MI with Cardiogenic Shock

 

Do you want to give fluids?

Tricky question! IV fluids helps BP in PE and Tamponade…but can be a poor idea in cardiogenic shock. Remember, in cardiogenic shock the heart can’t pump the fluid out leading to decreased venous return as demonstrated by JVD. Fluids in cardiogenic shock are generally a bad idea as they increase an already overloaded pre-load. Since her lungs are clear iIn this case, you can give a “100ml to 250ml bolus” [1] and reassess the patient for improved BP and the development of rales.

Once Basics Are Done

ECG and Echo. Yes, labs/cxr are also needed, but they won’t help you differentiate between the above three in a timely fashion.

Her Echo may have looked like this…

Apical 4
AP4

 

Parasternal Short

 

Parasternal Long

 

What findings are on these US images?
D sign, enlarged right ventricle, septal bowing. All concerning for right heart strain secondary to PE!

 

If the patient improves enough to get a CT...
IMG_20141224_184825_377 IMG_20141224_184836_050

 

Treatment?
IV Fluid, Heparin/LMWH, MICU, tpa given massive PE with hemodynamic instability. [2]

 

By Dr. Andrew Grock

 

Special thanks to Dr. Ian deSouza.

 

References
[1] Tintinalli’s 7th ed.

[2]Stavros V. Konstantinides et al. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). European Heart Journal (2014) 35, 3033–3080 doi:10.1093/eurheartj/ehu283

 

The views expressed on this blog are the author's own and do not reflect the views of their employer. Please read our full disclaimer here. Any references to clinical cases refer to patients treated at a virtual hospital, Janus General Hospital.
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andygrock

  • Resident Editor In Chief of blog.clinicalmonster.com.
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  • Resident at Kings County Hospital

3 comments for “Case #7, Answer

  1. Ian deSouza
    January 9, 2015 at 7:18 pm

    Careful with IV fluid and consider early use of norepinephrine.

    “Although patients with RV failure are often preload dependent, volume loading has the potential to overdistend the ventricles and cause increased wall tension, decreased contractility, increased ventricular interdependence, impaired LV filling, and reduced systemic cardiac output.”

    Piazza G and Goldhaber SZ. The acutely decompensated right ventricle. Chest 2005; 128: 1836-52.

    • Carl
      January 9, 2015 at 9:38 pm

      desouza, Oren Friedman was talking about limiting fluids this week at the critical care conference. However I’ve had hypotensive PE pts turn around quickly with 1 or 2 L of fluid.

  2. Carl
    January 9, 2015 at 9:36 pm

    Hey, couple points bout that echo.

    The RV is huge and very thin walled.
    The thickness of the RV wall can help you determine acute vs chronic elevated pulmonary pressures. You’ll get hypertrophy with the R wall with elevated pulmonary pressures just like you get a big LV wall from systemic hypertension. This is really big pressures and really acute.

    The Left Ventricular Ejection Fraction looks good and no real L sided wall abnormalities, which goes against Myocardial Infarction (not that you’re really scratching your head for this one, but this helps in equivocal cases). You can see the LV starting to collapse in late systole.

    With POC ultrasound, you should assess the lungs and IVC too while you’re looking at an undifferentiated dyspneic or hypotensive patients. Look for signs of fluid overload from a backed up LV and at the IVC to check for volume status (really only good in extremes of collapsing vs plethoric). I’m sure this lady’s IVC was huge.

    anyway, great case.

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