As you recall, we are discussing the case of a 23 year old female with an intentional, unknown overdose and subsequent hypotension and bradycardia. We had a brief discussion of the differential and are now going to discuss specific…
Tag: pharmacology
Morning Report: 12/23/2014
Dr. Youn presents today’s edition of Morning Report! NEBULIZED NALOXONE Weber, et al. Prehosp Emerg Care, 2mg naloxone nebulized with 3mL normal saline 105 cases- 22% complete response, 59% partial response, 19% no response No adverse events, no intubations…
Morning Report: 10/16/2014
Thanks to Dr. Gomes for another Morning Report! Beta-blocker Toxicity Receptors Beta 1- primarily in heart muscle. Activation –> increases HR, contractility and AV conduction. Decreased AV node refractoriness. Beta 2- primarily in bronchial and peripheral vascular smooth…
Morning Report: 9/30/2014
Today’s Morning Report is presented by Dr. Bart! Valproic Acid Background -Used for seizure disorders, BPD, migraine prophylaxis. -Peak concentrations at 6 hours except for enteric coated capsules. -Complications: -COMMON: Sedation, ataxia, weight gain, nausea, tremor, or hair loss…
Morning Report: 6/26/2014
Here’s Dr. Aluisio with today’s Morning Report!
Morning Report: 9/21/2012
Thanks Dr. Coquillon for today’s Morning Report! Alteplase: Mechanism of Action Recombinant human tissue-type plasminogen activator (t-PA); produces local fibrinolysis Promotes thrombolysis by converting plasminogen to plasmin which degrades fibrin and fibrinogen Pharmacokinetics Initial Half-Life: 5 minutes (free unbound…